In 1879, two scientists-Dr.Joseph Lawrence and Pharmacist Jordan Lambert—joined forces to create LISTERINE®, an effective formula made from three essential oils. More than 100 years later, those same three essential oils combine to pack a powerful punch against hard-to-reach germs that can cause plaque and bad breath. No other branded mouthwash offers this unique, essential-oil based formula. It penetrates deeply where brushing alone misses to reduce plaque and help keep your mouth clean and healthy. Our fixed combination of eucalyptol, menthol, and thymol continues to deliver results.